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Name of Symptom/Sign:
ICD-10 R25.3
ICD-O: {{{ICDO}}}
ICD-9 781.0
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A fasciculation (or "muscle twitching") is a small, local, involuntary muscle contraction(twitching) visible under the skin arising from the spontaneous discharge of a bundle of skeletal musclefibres. Fasciculations have a variety of cause, the majority of which are benign.


  • 1 Causes and risk factors
    • 1.1 Conditions
    • 1.2 Medications
  • 2 Treatment
  • 3 External links

Causes and risk factors


  • The most common cause of persistent fasciculations is benign fasciculation syndrome.
  • Werdnig-Hoffman disease
  • poisoningby organophosphates


Other risk factors may include the use of anticholinergicdrugs over long periods?in particular, ethanolaminessuch as Benadryl, used as an antihistamine and sleep aid, and Dramaminefor nausea and motion sickness. Persons with BFSmay experience paraesthesiashortly after taking such medication, then hours later as it wears off (especially upon awaking), fasciculation episodes begin.

Stimulants can cause fasciculations directly. These include caffeine, pseudoephedrine(Sudafed®), and albuterol/salbutamol (Proventil®, Combivent®, Ventolin®). Medications used to treat attention deficit disorderoften contain stimulants as well, and are common causes of benign fasciculations.


Inadequate magnesiumintake can cause fasciculations, especially after a magnesium loss due to severe diarrhea. Over-exertion is another risk factor for magnesium loss. As many as 80% of the population does not get the recommended daily amount of magnesium, this may be a common cause. Treatment is with supplements or increased intake of foods rich in magnesium, especially almonds and other nuts, and bananas. Ironically, magnesium supplements may result in diarrhea and more magnesium loss.

External links

  • GP Notebook
  • NIH/Medline
Retrieved from "http://en.wikipedia.org/Fasciculation"

This article is licensed under the GNU Free Documentation License.
It uses material from the http://en.wikipedia.org/wiki/Fasciculation Wikipedia article Fasciculation.

  All text is available under the terms of the GNU Free Documentation License